Author

Alex van Kaam

University Medical Center Groningen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alexander Martin HeberleiD· 1 shared Andrea OeckinghausiD· 1 shared Catalina Gaviria AgudeloiD· 1 shared Christy HongiD· 1 shared Floris FoijeriD· 1 shared Geneviève Lavoie· 1 shared Judith E. SimoniD· 1 shared Kathrin ThedieckiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander Martin HeberleORCID

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1 paper

Recent·Most cited

Increased activity of PRMT5-MEP50 complex improves survival of chromosomally unstable cancer cells by increasing tolerance to protein aggregation and proteotoxicity

Maria F. Suárez Peredo Rodríguez, Laura J. Jilderda, Catalina Gaviria Agudelo, Judith E. Simon, Alexander Martin Heberle, Alex van Kaam, Petra L. Bakker, Christy Hong, Maurits Roorda, Geneviève Lavoie, Philippe P. Roux, Andrea Oeckinghaus, Marcel A.T.M. van Vugt, Kathrin Thedieck, Floris Foijer

The paper shows that increased PRMT5-MEP50 complex activity helps aneuploid cancer cells survive by reducing protein aggregation and proteotoxicity.

bioRxiv · Sep 12, 2025 · PreprintCancer Biology