Author

Hisham Abdelmotilib

University of IowaORCID 0000-0001-8346-3366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew B. WestiD· 1 shared Arpine SokratianiD· 1 shared Ashley S. HarmsiD· 1 shared Aubrey M SchonhoffiD· 1 shared Cameron KeomanivongiD· 1 shared Enquan XuiD· 1 shared Georgina M. AldridgeiD· 1 shared Irene E. HarmseniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Andrew B. WestORCID

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2 papers

Recent·Most cited

NeuroscienceNeuroscience LettersPeer-reviewedNov 1, 2021

Cortical alpha-synuclein preformed fibrils do not affect interval timing in mice

Qiang Zhang, Hisham Abdelmotilib, Travis Larson…·Nandakumar Narayanan

This study investigates whether cortical injection of alpha-synuclein preformed fibrils (PFF) affects interval timing in mice, finding no consistent deficits despite synucleinopathy.

11 citations

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 4, 2020

Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses

Enquan Xu, Ravindra Boddu, Hisham Abdelmotilib…·Andrew B. West

The paper shows that α-synuclein fibrils activate LRRK2 kinase in monocyte-derived macrophages, linking LRRK2 mutations to pro-inflammatory responses in Parkinson's disease.

1 citation

humanmouse

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