Frem2 Knockout Mice Exhibit Fraser Syndrome Phenotypes and Neonatal Lethality Due to Bilateral Renal Agenesis
Rubina G. Simikyan, Xinyuan Zhang, Olga S. Strelkova…·Artur A. Indzhykulian
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Massachusetts Eye and Ear InfirmaryORCID 0000-0001-8365-6598Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Rubina G. Simikyan, Xinyuan Zhang, Olga S. Strelkova…·Artur A. Indzhykulian
Olga S. Strelkova, Richard T. Osgood, Chunjie Tian…·Artur A. Indzhykulian
This study shows PKHD1L1 is essential for maintaining stereocilia bundles, hearing function, and resilience to noise in mice, with loss leading to age-related hearing loss and susceptibility to noise damage.
Qiangzong Yin, Chih-Hsiang Yang, Olga S. Strelkova…·Oliver J. Rando
The paper reanalyzes sperm chromatin structure in mice, finding that prior studies were contaminated by cell-free chromatin, and identifies open loci associated with early development.
Melanie Holmgren, Michael E. Ravicz, Kenneth E. Hancock…·Lavinia Sheets
This study shows mechanical overstimulation causes acute injury and synapse loss in zebrafish neuromasts, but recovery occurs rapidly.