PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure.
Olga S. Strelkova, Richard T. Osgood, Chunjie Tian…·Artur A. Indzhykulian
This study shows PKHD1L1 is essential for maintaining stereocilia bundles, hearing function, and resilience to noise in mice, with loss leading to age-related hearing loss and susceptibility to noise damage.