Author

Melanie Holmgren

Washington University in St. LouisORCID 0000-0002-2541-4854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Lavinia SheetsiD· 2 shared Abhinav SuriD· 1 shared Adilenne Maese· 1 shared Allison E. GoldsteiniD· 1 shared Andrew E. M. DavisiD· 1 shared Aniket V. GoreiD· 1 shared Artur A. IndzhykulianiD· 1 shared Aurora KrausiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Lavinia SheetsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Anatomical and Molecular Characterization of the Zebrafish Meninges

Marina Venero Galanternik, Daniel Castranova, Ryan Gober, Tuyet A. T. Nguyen, Madeleine I. Kenton, Gennady Margolin, Aurora Kraus, Abhinav Sur, Louis Dye, Van N. Pham, Adilenne Maese, Melanie Holmgren, Aniket V. Gore, Bakary Samasa, Allison E. Goldstein, , Brant M. Weinstein

This paper characterizes the zebrafish meninges using single-cell transcriptomics, identifying a novel cell type essential for brain development.

bioRxiv · Apr 9, 2025 · PreprintDevelopmental Biology

Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish

Melanie Holmgren, Michael E. Ravicz, Kenneth E. Hancock, Olga S. Strelkova, Dorina Kallogjeri, Artur A. Indzhykulian, Mark E. Warchol, Lavinia Sheets

This study shows mechanical overstimulation causes acute injury and synapse loss in zebrafish neuromasts, but recovery occurs rapidly.

eLife · Oct 19, 2021Peer-reviewedNeuroscience

Influence of Mpv17 on hair-cell mitochondrial homeostasis, synapse integrity, and vulnerability to damage in the zebrafish lateral line

Melanie Holmgren, Lavinia Sheets

This study investigates how Mpv17 affects mitochondrial function and synapse integrity in zebrafish hair cells under stress, finding impaired mitochondrial activity leads to increased vulnerability and altered synaptic morphology.

Frontiers in Cellular Neuroscience · Aug 3, 2021Peer-reviewedNeuroscience