ImmunologyCell Death and DiseasePeer-reviewed
Neutrophil Reprogramming Underlie Vasculopathy and Lung Disease in Systemic Sclerosis
Norma Maugeri, Giuseppe Alvise Ramirez, Annalisa Capobianco…·Angelo Andrea Manfredi
This study identifies neutrophil reprogramming in systemic sclerosis (SSc) driven by HMGB1+ extracellular vesicles, leading to lung inflammation and fibrosis, and suggests therapeutic targeting of HMGB1.
1 citation