EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism
Elham Hasheminasabgorji, Huey‐Miin Chen, Taylor A. Gatesman, Subhi Talal Younes, Gabrielle Nobles, Farhang Jaryani, Heather Mao, Kwanha Yu, Benjamin Deneen, Voon Wee Yong, Michael D. Taylor, Sameer Agnihotri, Marco Gallo
This study investigates EZHIP mutations in pediatric brain tumors, showing their presence in new tumor types and revealing their role in neuronal-like gene programs and polyamine metabolism repression.
Acta Neuropathologica Communications · Nov 7, 2025Peer-reviewedCancer Biology