Hans‐Willem Snoeck

Co-optation of the regenerative role of type 2 alveolar cells in distal lung repair in mice by terminal airway epithelial cells in humans

This study shows human terminal airway epithelial cells regenerate alveolar type 1 cells without a type 2 intermediate, co-opting the mouse regenerative mechanism.

Mitofusin agonists improve the long-term repopulating activity of human cord blood HSCs after ex vivo culture

The paper shows mitofusin agonists enhance long-term repopulating activity of human cord blood HSCs in ex vivo culture without changing total nucleated cells or phenotypic HSCs.

Glycogen Synthase Kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture.

This study shows that GSK3 inhibition prevents multilineage maturation of hPSC-derived lung progenitors in 3D culture, while NOTCH and WNT signaling influence proximodistal cell fate specification.