Ya‐Wen Chen

This paper develops a pacemaker-driven human mini-heart using spatial multi-omics and stem-cell engineering to study cardiac conduction and drug discovery.

This study shows that blocking apoptosis in retinal organoids increases RGC survival but delays their development, highlighting apoptosis's role in regulating RGC quantity and dynamics.

Genipin rescues developmental and degenerative defects in familial dysautonomia and enhances neuron regeneration after injury.

This study develops a human pluripotent stem cell-derived organoid system to investigate vascular, mesenchymal, and epithelial co-development in lung and intestinal organoids, revealing organ-specific endothelial and mesenchymal features.

This study demonstrates that human pluripotent stem cell-derived progenitors can engraft in rat lungs and promote injury repair while preventing conditioning-induced damage.

This study shows that GSK3 inhibition prevents multilineage maturation of hPSC-derived lung progenitors in 3D culture, while NOTCH and WNT signaling influence proximodistal cell fate specification.