Tiago J. Dantas

Removal of the Ciliary Gate Allows Axoneme Extension in the Absence of Retrograde IFT

This study shows that removing the ciliary gate allows axoneme extension in IFT-A-deficient cilia by enabling passive diffusion and EV release of stalled IFT machinery.

CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization

This study identifies CDR2 as a dynein adaptor recruited by kinectin to regulate ER sheet organization and shows its role in centrosomal clustering and ER sheet stacking.

Glycogen Synthase Kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture.

This study shows that GSK3 inhibition prevents multilineage maturation of hPSC-derived lung progenitors in 3D culture, while NOTCH and WNT signaling influence proximodistal cell fate specification.