Author

Natalie Burkard

Universitätsklinikum WürzburgORCID 0000-0001-8386-4530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander García Ponce· 1 shared Anja K. E. HorniD· 1 shared Christian SiadjeuiD· 1 shared Christoph SchmitziD· 1 shared Daniela KugelmanniD· 1 shared Desalegn Tadesse EguiD· 1 shared Elisabeth S. ButziD· 1 shared Jens WaschkeiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alexander García Ponce

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1 paper

Recent·Most cited

Dsg2 truncation causes a lethal barrier breakdown in mice

Daniela Kugelmann, Elisabeth S. Butz, Alexander García Ponce, Mariya Yosifova Radeva, Jessica Neubauer, Matthias Hiermaier, Christian Siadjeu, Natalie Burkard, Desalegn Tadesse Egu, Anja K. E. Horn, Christoph Schmitz, Katri S. Vuopala, Outi Kuismin, Nicolas Schlegel, Jens Waschke

This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.

bioRxiv · Jul 1, 2024 · PreprintCell Biology