Author

Matthias Hiermaier

Anatomische AnstaltORCID 0000-0001-6035-6517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Jens WaschkeiD· 2 shared Alexander García Ponce· 1 shared Andreas Stengl· 1 shared Anja K. E. HorniD· 1 shared Brenda GerulliD· 1 shared Christian SiadjeuiD· 1 shared Christoph SchmitziD· 1 shared Daniela KugelmanniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Jens WaschkeORCID

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2 papers

Recent·Most cited

Cell BiologyActa PhysiologicaPeer-reviewedMay 31, 2026

Autoantibodies in patients with arrhythmogenic cardiomyopathy activate GSK-3β resulting in a loss of cardiomyocyte cohesion

Soumyata Pathak, Konstanze Stangner, Ellen Kempf…·Jens Waschke

This study identifies pathogenic autoantibodies against DSG2 in ACM patients that impair cardiomyocyte cohesion via GSK-3β activation.

DOI 10.1111/apha.70254

humanproteomics

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Cell BiologybioRxivPreprintJul 1, 2024

Dsg2 truncation causes a lethal barrier breakdown in mice

Daniela Kugelmann, Elisabeth S. Butz, Alexander García Ponce…·Jens Waschke

This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.

1 citation

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