Author

Alexander García Ponce

Anatomische Anstalt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 2

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Anja K. E. HorniD· 1 shared Carlijn Voermans· 1 shared Christian SiadjeuiD· 1 shared Christoph SchmitziD· 1 shared Daniela KugelmanniD· 1 shared Desalegn Tadesse EguiD· 1 shared Dietmar Vestweber· 1 shared Elisabeth S. ButziD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Anja K. E. HornORCID

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2 papers

Recent·Most cited

Dsg2 truncation causes a lethal barrier breakdown in mice

Daniela Kugelmann, Elisabeth S. Butz, Alexander García Ponce, Mariya Yosifova Radeva, Jessica Neubauer, Matthias Hiermaier, Christian Siadjeu, Natalie Burkard, Desalegn Tadesse Egu, Anja K. E. Horn, Christoph Schmitz, Katri S. Vuopala, Outi Kuismin, Nicolas Schlegel, Jens Waschke

This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.

bioRxiv · Jul 1, 2024 · PreprintCell Biology

Hematopoietic Stem And Progenitor Cells Use Podosomes To Transcellularly Home To The Bone Marrow.

Timo Rademakers, Marieke Goedhart, Mark Hoogenboezem, Alexander García Ponce, Jos van Rijssel, Maryna Samus, Michael Schnoor, Stefan Butz, Stephan Huveneers, Dietmar Vestweber, Martijn A. Nolte, Carlijn Voermans, Jaap D. van Buul

This study shows that VE-cadherin regulates bone marrow vascular permeability and hematopoietic stem and progenitor cell (HSPC) homing, with HSPCs using podosomes to transcellularly enter the bone marrow.

bioRxiv · Feb 22, 2018 · PreprintCell Biology