GenomicsProtein & CellPeer-reviewed
Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver
Bingbing He, Wenbo Peng, Jia Huang…·Pengyu Huang
This study demonstrates the use of CasRx-mediated RNA knockdown to modulate metabolic genes in mouse liver, showing efficient and reversible reduction of PCSK9 and cholesterol levels.
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