ImmunologyThe Journal of Experimental MedicinePeer-reviewed
A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling
Dominic P. Golec, Pedro Henrique Gazzinelli-Guimarães, Daniel Chauss…·Pamela L. Schwartzberg
The paper identifies a PI3Kδ-Foxo1-FasL signaling loop that disrupts Th2 differentiation and epigenetic regulation in CD4+ T cells.
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