Author

Yves De Repentigny

Ottawa Hospital Research InstituteORCID 0000-0001-8408-2442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Rashmi KotharyiD· 3 shared Michael A. RudnickiiD· 2 shared Uxía Gurriarán‐RodrígueziD· 2 shared Adriana Lucely RojasiD· 1 shared Aitor HierroiD· 1 shared Alberto MarinaiD· 1 shared David DatzkiwiD· 1 shared Ehsan JavandoostiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenetics

Rashmi KotharyORCID

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3 papers

Recent·Most cited

GeneticseLifePeer-reviewedFeb 20, 2025

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

Monique Marylin Alves de Almeida, Yves De Repentigny, Sabrina Gagnon…·Rashmi Kothary

This study investigates the impact of liver-specific SMN depletion in SMA mice, finding no motor neuron pathology but pancreatic changes and transient liver steatosis.

2 citations

mouseexperimental assay

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Molecular BiologyScience AdvancesPeer-reviewedDec 11, 2024

Wnt binding to Coatomer proteins directs secretion on exosomes independently of palmitoylation

Uxía Gurriarán‐Rodríguez, David Datzkiw, Leandro Radusky…·Michael A. Rudnicki

This study identifies the structural mechanism by which Wnt7a binds to exosomes for secretion, showing it is independent of palmitoylation and involves a dilysine motif interacting with COPB2.

19 citations

humanproteomics

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Cell BiologySkeletal MusclePeer-reviewedOct 11, 2024

Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filtration and Size Exclusion Chromatography

Uxía Gurriarán‐Rodríguez, Yves De Repentigny, Rashmi Kothary, Michael A. Rudnicki

The paper develops a protocol combining Tangential Flow Filtration and Size Exclusion Chromatography to isolate high-purity extracellular vesicles from muscle tissue, separating Wnt7a-bound EVs from free Wnt7a.

24 citations

mouseexperimental assay

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