Author

Brigitte Kerfélec

Centre National de la Recherche ScientifiqueORCID 0000-0001-8423-3423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Patrick ChamesiD· 3 shared Adrien Aimard· 1 shared Andréa Romette· 1 shared Aude Faucon· 1 shared Bastien Serrano· 1 shared Christophe FraisieriD· 1 shared Cléa Boursery· 1 shared Cristina Gonzàlez Gutierrez· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioengineering

Patrick ChamesORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringBiomaterialsPeer-reviewedNov 21, 2025

Functional targeting of Glypican-4 by a conformation-specific single-domain antibody

Remi Bonjean, Rossana Cuciniello, Brigitte Kerfélec…·Rosanna Dono

This paper identifies and characterizes nanobodies targeting human Glypican-4, showing they bind with high affinity and functionally inhibit hGPC4 activity in human pluripotent stem cells.

DOI 10.1016/j.biomaterials.2025.123864

humanproteomics

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NeuroscienceJournal of Controlled ReleasePeer-reviewedOct 17, 2025

Novel VHH targeting a unique TfR1 epitope for efficient cross-species delivery of drugs in the CNS

Marion David, Romy Cohen, Diane Beuzelin…·Michel Khrestchatisky

This study identifies cross-species reactive VHHs targeting a novel TfR1 epitope, enabling efficient BBB crossing for CNS drug delivery.

8 citations

mouserat

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BiophysicsACS NanoPeer-reviewedJan 10, 2025

Decoupling individual host response and immune cell engager cytotoxic potency

Cristina Gonzàlez Gutierrez, Adrien Aimard, Martine Biarnes‐Pelicot…·Laurent Limozin

The paper measures cytotoxicity of bispecific antibodies using NK cells and introduces a model to decouple host response from engager characteristics.

7 citations

humanproteomics

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