Baptiste Alric

The paper introduces two microfluidic devices for applying and measuring growth-induced pressure on microbes, enabling single-cell imaging and bulk biochemical analysis under controlled conditions.

This study shows that bacterial growth under confinement leads to increased turgor pressure, which disrupts division and protein synthesis, and activates the Rcs pathway, with implications for infection physiology.

This study shows that VEGF-A and VEGF-C co-stimulation induces lymphatic vessel polarization without shear stress, revealing a mechanism involving VEGFR2/VEGFR3 activation and geometrically-encoded stiffness.

The paper shows that intraluminal pressure rapidly strengthens endothelial barriers through actin reorganization and paracellular gap closure, lasting up to 30 minutes.

This study measures intracellular dry mass density in yeast under growth-induced pressure and finds it correlates with macromolecule accumulation and osmolyte concentration.