Author

Ninian N. Lang

British Heart FoundationORCID 0000-0001-8441-6887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A.D. SmalliD· 1 shared Alasdair David HendersoniD· 1 shared Alastair J. GemmelliD· 1 shared Alexander S Johnston· 1 shared Ali Ali Mohamed ElbassioniiD· 1 shared Anmar RaheemiD· 1 shared Ashley Bradley· 1 shared Balaji VenugopaliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A.D. SmallORCID

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2 papers

Recent·Most cited

Targeting Runx1 protects against heart failure with preserved ejection fraction

Ali Ali Mohamed Elbassioni, Anmar Raheem, Jian Hua Song, Alexander S Johnston, Cara Trivett, Hong Lin, Haobo Zhang, Ashley Bradley, Erin Higgins, Leanne Mooney, Yen Chin Koay, Dylan O’Toole, Pawel Herzyk, Colin Nixon, Karen Blyth, , Eilidh A. MacDonald

This study shows that inhibiting Runx1 protects against heart failure with preserved ejection fraction in mice by improving diastolic function and reducing hypertrophy and pulmonary edema.

bioRxiv · Jan 24, 2025 · PreprintPhysiology

Arterial effects of anthracycline: structural and inflammatory assessments in non-human primates and lymphoma patients using 18F-FDG positron emission tomography

Stephen H Rankin, Caitlin Fountain, Alastair J. Gemmell, Daire Quinn, Alasdair David Henderson, J. D. McClure, A.D. Small, Balaji Venugopal, Pam McKay, Piotr J. Slomka, David Colville, Mark Colquhoun Petrie, Giselle C. Meléndez, Ninian N. Lang

This study evaluates anthracycline-induced arterial injury in non-human primates and lymphoma patients using histopathology and PET/CT, finding increased fibrosis in primates but no inflammation in patients.

Clinical Science · Dec 16, 2024Peer-reviewedPharmacology & Toxicology