ImmunologybioRxivPreprint
Display of clustered antigen by follicular dendritic cells tunes B-cell receptor activation
Ali Shahrokhtash, Hiroaki Ogasawara, Kristian Savstrup Kastberg…·Duncan S. Sutherland
The paper shows that antigen clustering on follicular dendritic cells enhances B-cell receptor activation through geometric control of tyrosine phosphatase exclusion.
DOI 10.1101/2025.11.05.686827