Author

See‐Yeun Ting

National Taiwan UniversityORCID 0000-0001-8472-7204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

Po-Yin CheniD· 3 shared Chia-En TsaiiD· 2 shared Yung-Chih CheniD· 2 shared Chao-Yuan Hu· 1 shared Chien‐Ling LiniD· 1 shared Chih‐Feng WuiD· 1 shared Chih‐Wen YangiD· 1 shared Chuan KuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

Po-Yin ChenORCID

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4 papers

Recent·Most cited

Structural and Functional Principles of Hcp-Mediated Antibacterial Toxin Delivery by the Type VI Secretion System

Po-Yin Chen, Yung‐Chih Chen, Chun-Hsiung Wang, Jia-Ying Su, Chien‐Ling Lin, See‐Yeun Ting

This study investigates how Hcp in the T6SS selectively delivers diverse effectors using structural and functional analyses.

bioRxiv · Aug 3, 2026 · PreprintMicrobiology

Abiotic cues modulate exopolysaccharides to influence type VI secretion system-mediated antagonism

Yi-Chien Wang, Li‐Kang Sung, Chih‐Feng Wu, Jeff H. Chang, See‐Yeun Ting, Erh‐Min Lai

This study shows abiotic factors modulate exopolysaccharides in Agrobacterium fabrum, affecting T6SS-mediated antagonism by altering physical distance and attack efficacy.

bioRxiv · Jun 18, 2026 · PreprintMicrobiology

An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE

Pin-Yi Song, Chia-En Tsai, Yung-Chih Chen, Yuwen Huang, Po-Pang Chen, Tzu‐Haw Wang, Chao-Yuan Hu, Po-Yin Chen, Chuan Ku, Kuo‐Chiang Hsia, See‐Yeun Ting

The paper identifies Cpe1, an interbacterial cysteine protease toxin from E. coli, which inhibits bacterial growth by cleaving type II DNA topoisomerases GyrB and ParE, disrupting DNA replication and chromosome segregation.

PLoS Biology · May 27, 2025Peer-reviewedMicrobiology

Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism

Chia-En Tsai, Feng-Qi Wang, Chih‐Wen Yang, Lingli Yang, T. V. P. Nguyen, Yung-Chih Chen, Po-Yin Chen, Ing‐Shouh Hwang, See‐Yeun Ting

The paper shows that phage resistance in Salmonella enterica leads to fitness loss when co-cultured with competitor bacteria due to LPS deficiency and increased susceptibility to T6SS.

The EMBO Journal · Mar 10, 2025Peer-reviewedMicrobiology