Jonathan Friedman

The paper shows that the human gut microbiota recovers to an individual-specific state after antibiotics, not to a generic healthy state.

The paper shows that boom-and-bust growth regimes reduce selection from species interactions that affect growth rates but not from interactions that affect mortality.

This study integrates genomic, transcriptomic, and metabolomic analyses to reveal temporally coordinated biosynthetic programs in the rare actinomycete Saccharomonospora xinjiangensis XJ-54 that produce antifungal compounds.

Across 40 carbon-nitrogen environments, six matched E. coli and B. subtilis amino acid auxotrophs show context-dependent auxotrophy, while auxotroph type predicts cross-feeding yield better than environment.

This study evaluates the antifungal potential and biosynthetic diversity of Saccharomonospora strains, identifying novel bioactive metabolites and uncharacterized gene clusters.

This study shows that cross-resistance, not mode of action, determines the effectiveness of antimicrobial peptide combinations in delaying resistance evolution.

This study shows that evolutionary rescue in a bacterial mutualism occurs when one strain reverts to metabolic autonomy, allowing the community to survive lethal stresses despite the other strain's sensitivity.

The paper extends the Marginal Value Theorem to simple organisms with limited sensory abilities, showing that adjusting feeding speed based on environmental average feeding rates improves foraging efficiency.

This study identifies bacterial isolates capable of degrading indole-3-acetic acid (IAA) from Arabidopsis and rice roots, revealing their functional roles and association with IAA producers.