Andreas Prokop

This study shows that Miro-TRAK interaction is not required for bulk mitochondrial transport in Drosophila, as mutant flies are viable and neurons show normal axonal mitochondria, though they exhibit age-related motor deficits and reduced lifespan.

This study identifies novel plasma proteins associated with KIF5A-linked SPG10 and ALS using targeted proteomics, revealing distinct proteomic signatures and potential biomarkers.

The paper identifies microtubule-curling as a marker of axonal atrophy by analyzing gene deficiencies in Drosophila neurons, revealing two distinct mechanisms linked to neurodegeneration.

The paper assesses the impact of 13 mitochondrial factors on axonal microtubule organization in Drosophila neurons to identify mechanisms linking mitochondrial dysfunction to neurodegeneration.

The paper investigates how both loss and gain of kinesin functions lead to axonal degeneration through microtubule curling in Drosophila neurons.

This study investigates the role of spectraplkin proteins in axon growth and maintenance, revealing that their function depends on a balanced interaction with F-actin and that they have actin-independent roles in microtubule bundling.

The paper investigates the role of periodic actin structures (PMS) in maintaining microtubules in axons using Drosophila genetics and microscopy, finding that PMS supports microtubule organization and polymerization.

This paper reviews the molecular mechanisms regulating microtubule plus end dynamics in neuronal axons and discusses challenges in integrating this knowledge into a conceptual framework.

The paper describes a strategy for developing high-quality, multi-audience science outreach initiatives by setting clear objectives and building shared resources through collaboration.