Milli Owens

The Interaction Between Miro and TRAK is not Required for Bulk Mitochondrial Trafficking

This study shows that Miro-TRAK interaction is not required for bulk mitochondrial transport in Drosophila, as mutant flies are viable and neurons show normal axonal mitochondria, though they exhibit age-related motor deficits and reduced lifespan.

Microtubule curling as an efficient readout to uncover fundamental concepts of axonal cell biology and neurodegeneration

The paper identifies microtubule-curling as a marker of axonal atrophy by analyzing gene deficiencies in Drosophila neurons, revealing two distinct mechanisms linked to neurodegeneration.

Assessing impacts of mitochondrial dysfunction on axonal microtubule bundles as potential mechanism in neurodegeneration

The paper assesses the impact of 13 mitochondrial factors on axonal microtubule organization in Drosophila neurons to identify mechanisms linking mitochondrial dysfunction to neurodegeneration.

Different mechanisms link gain and loss of kinesin functions to axonal degeneration

The paper investigates how both loss and gain of kinesin functions lead to axonal degeneration through microtubule curling in Drosophila neurons.