Author

Julia F. Riley

Aligning Science Across Parkinson'sORCID 0000-0001-8518-9786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Erika L.F. HolzbauriD· 2 shared Aaron M.N. JoineriD· 1 shared Aniketh BishnuiD· 1 shared Charity V RobbinsiD· 1 shared Ian G. GanleyiD· 1 shared Isaac J. AlleniD· 1 shared James H. HurleyiD· 1 shared Minghao CheniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Erika L.F. HolzbaurORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 10, 2026

Structural basis for the selective inhibition of the PI3KC3-C2 complex by Rubicon in endolysosome maturation and mitophagy

Minghao Chen, Aniketh Bishnu, Yongjia Duan…·James H. Hurley

This paper determines the cryo-EM structure of the PI3KC3-C2 complex with Rubicon's PIKBD domain, revealing how Rubicon selectively inhibits PI3KC3-C2 to regulate endolysosome maturation and mitophagy.

DOI 10.64898/2026.08.07.743589

humancryo-EM

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 13, 2026

PINK1/Parkin-dependent mitophagy mediates astrocytic inflammatory responses to mitochondrial damage

Julia F. Riley, Charity V Robbins, Erika L.F. Holzbaur

This study shows that mitochondrial damage in astrocytes triggers inflammatory responses via PINK1/Parkin-dependent mitophagy, leading to cytokine release and neuroinflammation in Parkinson's disease.

2 citations

mousehuman

𝕏 PostBluesky