Shoaib Ajaib

This study uses imaging mass cytometry to analyze changes in glioblastoma tumor microenvironment before and after treatment, finding increased normal brain cells and altered cellular interactions post-treatment.

GBMPurity is a deep learning tool that estimates glioblastoma tumour purity from bulk RNA-seq data, outperforming existing methods and revealing subtype-specific purity patterns.

This paper introduces a method to profile the transcriptome of live cells over time, showing treatment induces transcriptionally stable cells in glioblastoma.