Asa A. Brockman

Velociraptor identifies and searches for novel cell types across platforms using hallmark feature sets, revealing new biological insights in glioblastoma and immunology.

This study uses imaging mass cytometry to analyze changes in glioblastoma tumor microenvironment before and after treatment, finding increased normal brain cells and altered cellular interactions post-treatment.

The paper develops a machine learning tool to identify balloon cells in TSC brain tissues using imaging mass cytometry and a custom antibody panel.

This study identifies IL-8 as a key factor instructing macrophage identity in glioblastoma, showing IL-8 is necessary for generating CD32+ M_IL-8 macrophages in tumors contacting the lateral ventricle.

This paper shows that Jedi-1-mediated phagocytosis by microglia in the V-SVZ promotes neurogenesis by suppressing inflammatory pathways, and its loss leads to neuroinflammation and reduced neural precursor proliferation.

This study identifies the role of 4EBP1/2 dephosphorylation in inducing quiescence in embryonic neural stem cells, offering insights into adult brain development and potential therapeutic strategies.

CASSATT processes cycIHC data to align images, segment nuclei, and analyze spatial cell interactions and neighborhoods.

The paper develops a 3D-printing protocol and open-source software for creating standardized head molds for stereotaxic injections in neonatal mice, enabling reproducible and rapid mold generation across labs.