Arif Ibrahim Ardisasmita

The paper identifies how differential TCF7L2/LEF1 binding specificity of {beta}-catenin shapes distinct gene regulatory outcomes in liver tumors.

This study develops hepatocyte-like liver organoids (HeLLOs) that closely mimic mature hepatocyte functions and outperform existing models in drug toxicity testing and disease modeling.

This study develops a method to generate and expand hepatobiliary organoids from adult human hepatocytes, which retain liver function and can model liver diseases.