Author
University of LiverpoolORCID 0000-0001-8528-1021Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Adam Albanese, Leonard A. Daly, Katrin Prost-Fingerle…·Sónia Rocha
This study shows that phosphorylation at S345 converts HIF-2α from a transcription factor to an RNA-binding protein, altering its function in hypoxia response.
Dilem Shakir, Michael Batie, Chun-Sui Kwok…·Sónia Rocha
The paper identifies NF-kappaB-dependent gene expression changes under hypoxia, showing its role in repression of hypoxia-downregulated genes and regulation of oxidative phosphorylation.
Rebecca Gilley, Andrew M. Kidger, Graham W. Neill…·Simon J. Cook
This study shows RAF inhibitors activate the integrated stress response via direct GCN2 activation, independent of ERK1/2, leading to ATF4 and CHOP expression.