Paul M. Seidler

This paper develops a small molecule that disaggregates tau fibrils and oligomers, reduces pathology, and preserves function in a tauopathy mouse model.

This study shows cPLA2 overactivation is linked to synaptic loss and cognitive decline in Alzheimer's disease through increased eicosanoids and altered synaptic marker interactions.

This study shows that Oolonghomobisflavans reduce tau fibrils and improve health in Alzheimer's models.