James A. Coffman

The paper develops a zebrafish model of accelerated muscle atrophy by inducing Atrogin-1 expression, showing muscle degeneration, locomotion dysfunction, and neurodegenerative effects.

The paper investigates the long-term effects of chronic cortisol exposure during zebrafish embryonic development, finding persistent neuroendocrine dysregulation and altered gene expression in adulthood.

The paper identifies Klf9 as a key regulator of the transcriptomic response to glucocorticoid receptor activity in zebrafish larvae, showing it mediates proinflammatory gene upregulation under chronic cortisol exposure.