Romain Menard

Mesenchymal-derived neural progenitors underlie local insulin production and neuronal transdifferentiation during retina regeneration

This study identifies mesenchymal-derived neural progenitors that transdifferentiate into retinal ganglion cells in zebrafish after neuronal ablation, revealing a novel mechanism for retinal regeneration.

Sexually Dimorphic Response to Dietary Restriction-induced Longevity and Muscle Rejuvenation in Nothobranchius furzeri.

This study shows that intermittent fasting improves muscle health and extends lifespan in both sexes of African turquoise killifish, with sex-specific molecular and cellular changes.

Zebrafish genetic model of neuromuscular degeneration associated with Atrogin-1 expression

The paper develops a zebrafish model of accelerated muscle atrophy by inducing Atrogin-1 expression, showing muscle degeneration, locomotion dysfunction, and neurodegenerative effects.

The small molecule ML233 is a direct inhibitor of tyrosinase function

This study identifies ML233 as a potent and safe tyrosinase inhibitor that reduces melanin production in zebrafish and murine melanoma cells without significant toxicity.

Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis

The paper shows that leukemia cells secrete apelin, which promotes clonal expansion of niche endothelial cells and drives leukemogenesis in zebrafish.