Author

Luke S. Myers

Texas A&M UniversityORCID 0000-0001-8554-0994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:plant (other)· 3 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:imaging· 1 Organism:non-human primate· 1

Frequent Co-Authors

Sarah ChristianiD· 4 shared Scott V. DindotiD· 4 shared Anne E. AndersoniD· 3 shared Alasdair J. TayloriD· 2 shared Annalise SchlaferiD· 2 shared David Jay SegaliD· 2 shared Edwin J. WeeberiD· 2 shared Jill L. SilvermaniD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Sarah ChristianORCID

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Author profile →

4 papers

Recent·Most cited

Elevated Delta Power in a Maternal UBE3A-Deletion Pig Model of Angelman Syndrome

Luke S. Myers, Tanner G. Monk, Luis A. Martinez, Alasdair J. Taylor, Sarah Christian, Anne E. Anderson, Scott V. Dindot

The paper evaluates delta power abnormalities in a maternal UBE3A-deletion pig model of Angelman syndrome using EEG, finding elevated delta power during wakefulness and reduced transitions to sleep.

Brain and Development · Aug 16, 2026Peer-reviewedNeuroscience

MRI-Based Quantification of Central Nervous System Tissue and Cerebrospinal Fluid Volumes in Developing Pigs

Luke S. Myers, John F. Griffin, Sarah Christian, Scott V. Dindot

This study quantifies CNS tissue and CSF volumes in developing pigs using MRI, revealing age-related changes in CSF distribution.

bioRxiv · Oct 21, 2025 · PreprintNeuroscience

A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human condition

Luke S. Myers, Sarah Christian, Sean G. Simpson, Renan B. Sper, Clint Taylor, Laura Montes, Thomas Jepp, Daniela Ramos, Livia Schuller, Kranti Konganti, Wade O. Friedeck, Ozair Habib, McKaela Hodge, Alasdair J. Taylor, Ashley Coffell, , Scott V. Dindot

This paper describes a pig model of Angelman syndrome that mirrors early developmental symptoms observed in humans.

Proceedings of the National Academy of Sciences · Jul 21, 2025Peer-reviewedGenetics

Development of an ASO therapy for Angelman syndrome by targeting an evolutionarily conserved region at the start of the UBE3A-AS transcript

Scott V. Dindot, Sarah Christian, William J. Murphy, Allyson Berent, Jennifer Panagoulias, Annalise Schlafer, Johnathan L. Ballard, Kamelia Radeva, Ruth Robinson, Luke S. Myers, Thomas Jepp, Hillary Shaheen, Paul Hillman, Kranti Konganti, Andrew Hillhouse, , Jill L. Silverman

This paper describes the development of an antisense oligonucleotide (ASO) therapy targeting the UBE3A-AS transcript to reactivate paternal UBE3A expression in Angelman syndrome models.

Science Translational Medicine · Mar 22, 2023Peer-reviewedGenetics