The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA
Ryota Kurimoto, Tomoki Chiba, Yoshiaki Ito, Takahide Matsushima, Yuki Yano, Kohei Miyata, Yuka Yashiro, Tsutomu Suzuki, Kozo Tomita, Hiroshi Asahara
The paper identifies TruB1 as a regulator of let-7 miRNA maturation and function, showing it enhances let-7 processing through direct interaction with pri-let-7.
The EMBO Journal · Sep 14, 2020Peer-reviewedMolecular Biology