Weihong Qi

Non-coding DNA dictates cell size and impairs fitness by sequestering RNA polymerase

This study shows that non-coding DNA in yeast affects cell size and fitness by sequestering RNA polymerase, reducing transcript levels and impairing growth.

Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids

This study uses single-cell long-read sequencing to analyze transcriptomes of ccRCC organoids, identifying novel transcripts and highlighting cell-specific alternative splicing events.

Comparison of Single-cell Long-read and Short-read Transcriptome Sequencing of Patient-derived Organoid Cells of ccRCC: Quality Evaluation of the MAS-ISO-seq Approach

AlcoR: alignment-free simulation, mapping, and visualization of low-complexity regions in biological data

AlcoR is a tool for simulating, mapping, and visualizing low-complexity regions in genomic and proteomic sequences, demonstrating high efficiency and accuracy on synthetic and natural data.

The haplotype-resolved chromosome pairs and transcriptome of a heterozygous diploid African cassava cultivar

This study presents haplotype-resolved chromosome pairs and transcriptome of a diploid African cassava cultivar using HiFi sequencing and Hi-C, revealing structural variations and allele-specific expression patterns.