Author

Skyler A. Briggs

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & TechnologyORCID 0000-0001-8593-5638Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

James M. BurkeiD· 2 shared Alexander M. PriceiD· 1 shared Amber R. N. AbbottiD· 1 shared Bo LiiD· 1 shared Cameron Stone· 1 shared Chung-Wei FuiD· 1 shared Connor C. WangiD· 1 shared Eva L. Agostino· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

James M. BurkeORCID

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2 papers

Recent·Most cited

Cell BiologyPLoS PathogensPeer-reviewedJul 24, 2026

Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants

Robert T. Steinbock, Orlando Bonito Scudero, Joseph M. Dybas…·Matthew D. Weitzman

This study shows adenovirus mutants differentially activate dsRNA sensors, leading to distinct RNP granule assemblies via PKR and OAS3/RNase L pathways.

DOI 10.1371/journal.ppat.1014452

humanproteomics

𝕏 PostBluesky

BiochemistryJournal of the American Chemical SocietyPeer-reviewedMar 6, 2026

Macrocyclic Peptides Containing an Imidazopyridinium (IP+) Unit Display Enhanced Passive Cell Permeability

Bo Li, Joshua Parker, Skyler A. Briggs…·Thomas J. Kodadek

This study shows that adding an imidazopyridinium (IP+) unit to macrocyclic peptides enhances their passive membrane permeability, enabling them to enter cells and inhibit intracellular targets like p53-MDM2.

7 citationstop 1%

experimental assaydrug response / drug discovery

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