Author

Alexander M. Price

The Wistar InstituteORCID 0000-0003-4654-4604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Assay:proteomics· 1

Frequent Co-Authors

Matthew D. WeitzmaniD· 2 shared Susan Reich WeissiD· 2 shared Alexa B. R. McIntyreiD· 1 shared Alison YuiD· 1 shared Amber R. N. AbbottiD· 1 shared Angus C. WilsoniD· 1 shared Ashley N. Della FeraiD· 1 shared Cameron Stone· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Matthew D. WeitzmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants

Robert T. Steinbock, Orlando Bonito Scudero, Joseph M. Dybas, Amber R. N. Abbott, Katarzyna Kulej, Richard Lauman, Holly Chan, Eva L. Agostino, Namrata Kumar, Cameron Stone, Skyler A. Briggs, Nicholas A. Parenti, Yize Li, James M. Burke, Susan Reich Weiss, , Matthew D. Weitzman

This study shows adenovirus mutants differentially activate dsRNA sensors, leading to distinct RNP granule assemblies via PKR and OAS3/RNase L pathways.

PLoS Pathogens · Jul 24, 2026Peer-reviewedCell Biology

Inhibition of RNA splicing is a novel therapeutic strategy for disruption of nuclear replicating viruses

Lorenzo Serra, Claire M O'Brien, Molly R. Patterson, Clayton J. Otter, Alison Yu, Reyes Acosta, Daniel T. Claiborne, Susan Reich Weiss, Alexander M. Price

This study shows that inhibiting RNA splicing reduces viral replication in splicing-dependent viruses like adenovirus, HSV-1, and influenza A, suggesting a new antiviral strategy.

bioRxiv · Jun 27, 2026 · PreprintMicrobiology

Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing

Alexander M. Price, Katharina E. Hayer, Alexa B. R. McIntyre, Nandan S. Gokhale, Jonathan S. Abebe, Ashley N. Della Fera, Christopher E. Mason, Stacy M. Horner, Angus C. Wilson, Daniel Pearce Depledge, Matthew D. Weitzman

The paper uses direct RNA long-read sequencing to show m6A modifications on adenovirus RNA are necessary for efficient splicing.

Nature Communications · Nov 26, 2020Peer-reviewedMolecular Biology