Yukako Fujinaga

The paper shows that infant acquisition of Stickland-metabolizing bacteria prevents Clostridium botulinum infection by competing for amino acids.

This study identifies LRP1 as the receptor for L-PTC/BOkra to enter the gut, showing HA binds to LRP1 via N-glycans and facilitates transcytosis.

This study develops an antibiotic-treated mouse model to study intestinal botulism, showing that Cb colonization and BoNT/A accumulation lead to disease progression.

The paper shows that fucosylation of intestinal mucin determines the entry routes and oral toxicity of botulinum toxin complexes.

The paper optimizes genetic manipulation protocols for group I Clostridium botulinum and develops a novel conjugal suicide vector for efficient genome editing.