Takuhiro Matsumura

The paper shows that infant acquisition of Stickland-metabolizing bacteria prevents Clostridium botulinum infection by competing for amino acids.

This study identifies LRP1 as the receptor for L-PTC/BOkra to enter the gut, showing HA binds to LRP1 via N-glycans and facilitates transcytosis.

This study develops an antibiotic-treated mouse model to study intestinal botulism, showing that Cb colonization and BoNT/A accumulation lead to disease progression.

The paper shows that fucosylation of intestinal mucin determines the entry routes and oral toxicity of botulinum toxin complexes.