Kazuki Saito

The paper shows that infant acquisition of Stickland-metabolizing bacteria prevents Clostridium botulinum infection by competing for amino acids.

This study develops an antibiotic-treated mouse model to study intestinal botulism, showing that Cb colonization and BoNT/A accumulation lead to disease progression.

The paper optimizes genetic manipulation protocols for group I Clostridium botulinum and develops a novel conjugal suicide vector for efficient genome editing.

The paper identifies SmrB as a factor that cleaves mRNAs upstream of stalled ribosomes in bacteria, promoting ribosome rescue through ribosome collisions.

MS-DIAL 4 provides a comprehensive lipidome atlas with retention time, collision cross section, and MS/MS data to standardize and accelerate lipidomics research.