Author

Hugo Belda

The Francis Crick InstituteORCID 0000-0001-8628-9455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Moritz TreeckiD· 3 shared David T. JonesiD· 2 shared Malgorzata BronceliD· 2 shared Stephanie D. NofaliD· 2 shared Andrew G. PurkissiD· 1 shared Andrew PowelliD· 1 shared Antoine ClaessensiD· 1 shared Benoît GamainiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

Moritz TreeckORCID

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3 papers

Recent·Most cited

BiochemistryPLoS PathogensPeer-reviewedJul 29, 2026

FIKK1, a member of the FIKK kinase family, phosphorylates VAR2CSA and regulates adhesion of Plasmodium falciparum-infected erythrocytes to the placental receptor CSA

Benoît Gamain, Jean‐Philippe Semblat, Heledd Eavis…·Dominique Dorin

This study identifies FIKK1 as a kinase that phosphorylates VAR2CSA, enhancing its binding to CSA and promoting placental malaria virulence.

DOI 10.1371/journal.ppat.1014108

plant (other)experimental assay

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Cell BiologyeLifePeer-reviewedMay 13, 2026

Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell

David T. Jones, Hugo Belda, Malgorzata Broncel…·Moritz Treeck

The paper shows that febrile heat stress increases cytoadhesion in Plasmodium falciparum-infected red blood cells by enhancing surface protein trafficking, including PfEMP1 and PSAC.

3 citations

humanproteomics

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MicrobiologyNature MicrobiologyPeer-reviewedMay 19, 2025

Evolution and inhibition of the FIKK effector kinase family in P. falciparum

Hugo Belda, David Bradley, Evangelos Christodoulou…·Moritz Treeck

This study investigates the evolution and inhibition of FIKK kinases in P. falciparum, showing they can be inhibited by a single compound.

5 citations

humandeep learning

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