Sfh3 is a sterol-modulated PI/PI4P transfer protein that confers azole resistance in yeast by specifically mediating lanosterol/PI exchange
Amazigh Hamaï, Pauline Perne, Abhishek Tripathi…·Guillaume Drin
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Centre National de la Recherche ScientifiqueORCID 0000-0001-8632-1339Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Amazigh Hamaï, Pauline Perne, Abhishek Tripathi…·Guillaume Drin
Alicia Fabbre, Camille Syska, Heitor Gobbi Sebinelli…·Guillaume Drin
This study shows that Osh6 requires Ist2 for efficient phosphatidylserine transfer between membranes, revealing a functional partnership between an LTP and a membrane tethering/scramblase protein.
Bradley S. Jones, Vikram Pareek, Daniel D. Hu…·Patricia A. DiGiuseppe Champion
This study identifies N-acetyltransferases in M. marinum that link iron uptake, aminoglycoside resistance, and virulence lipid production, revealing their multifunctional roles in pathogenesis.
Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma…·Alenka Čopič
This study identifies Ist2 as the first dedicated ER phospholipid scramblase in yeast and shows its role in ER membrane remodeling.