Sfh3 is a sterol-modulated PI/PI4P transfer protein that confers azole resistance in yeast by specifically mediating lanosterol/PI exchange
Amazigh Hamaï, Pauline Perne, Abhishek Tripathi…·Guillaume Drin
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Centre National de la Recherche ScientifiqueORCID 0000-0002-3484-4581Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Amazigh Hamaï, Pauline Perne, Abhishek Tripathi…·Guillaume Drin
Céline Knorr, Mehdi Zouiouich, Julie Eichler…·Fabien Alpy
This study identifies MOSPD2-STARD3 as a functional unit regulating late endosome/lysosome dynamics and cholesterol homeostasis through selective interaction at ER contact sites.
Julie Eichler, Corinne Wendling, Sophie Huver…·Fabien Alpy
This study identifies GSK3 as the kinase responsible for phosphorylating STARD3, which regulates ER-LE/Lys contacts and endosome positioning through a phosphorylation switch.
Alicia Fabbre, Camille Syska, Heitor Gobbi Sebinelli…·Guillaume Drin
This study shows that Osh6 requires Ist2 for efficient phosphatidylserine transfer between membranes, revealing a functional partnership between an LTP and a membrane tethering/scramblase protein.
Noha Al-Qatabi, Maud Magdeleine, Sophie Pagnotta…·Guillaume Drin
This study characterizes two atypical BAR domain-containing proteins in Toxoplasma gondii, revealing their distinct membrane-binding properties and roles in parasite trafficking.