Alenka Čopič

This study compares the 4-helix bundle domains of perilipin 3 and perilipin 4 to identify structural features that influence their binding to lipid droplets.

The paper shows that the CE/TG ratio determines lipid droplet size and phase behavior, influencing their function and disease relevance.

This study shows that Osh6 requires Ist2 for efficient phosphatidylserine transfer between membranes, revealing a functional partnership between an LTP and a membrane tethering/scramblase protein.

This study shows that a genetic expansion in PLIN4 repeats leads to amyloid fibril formation, contributing to myopathy.

This study identifies Ist2 as the first dedicated ER phospholipid scramblase in yeast and shows its role in ER membrane remodeling.

The paper investigates how different human perilipins bind to lipid droplets by showing their varying affinities based on surface tension and lipid composition.