Rae Silver

The paper identifies portal neurovascular connections between sensory circumventricular organs and adjacent brain tissue, enabling direct diffusible signaling.

The paper identifies a new vascular portal pathway from the SCN to the OVLT, showing circadian-regulated blood flow and AVP transport, suggesting a mechanism for circadian signaling.

The paper examines the suprachiasmatic nucleus (SCN) to identify intermediate structures called phaseomes through phase differences and connectivity gradients, revealing anisotropy in network organization.

The paper describes a new portal system connecting the suprachiasmatic nucleus (SCN) and organum vasculosum of the lamina terminalis (OVLT) in the brain, suggesting new routes for secreted signals and redefining brain communication pathways.