Yifan Yao

The paper identifies portal neurovascular connections between sensory circumventricular organs and adjacent brain tissue, enabling direct diffusible signaling.

The paper identifies a new vascular portal pathway from the SCN to the OVLT, showing circadian-regulated blood flow and AVP transport, suggesting a mechanism for circadian signaling.

The paper describes a new portal system connecting the suprachiasmatic nucleus (SCN) and organum vasculosum of the lamina terminalis (OVLT) in the brain, suggesting new routes for secreted signals and redefining brain communication pathways.