Peter A. Keyel

This study identifies GP63 as a protease that activates aerolysin toxin in Leishmania major, revealing a mechanism of bacterial competition in the sandfly midgut.

This study identifies Vav2 as the master regulator of Ca2+-dependent repair against bacterial pore-forming toxins in necrotizing soft tissue infections.

This study investigates how Leishmania major resists cholesterol-dependent cytolysins by analyzing the role of membrane components in toxin binding and cytotoxicity.

This study investigates how cells repair damage from the fungal toxin candidalysin compared to bacterial pore-forming toxins, finding distinct Ca2+-dependent mechanisms and roles for MEK and annexins.