Author

Timothy J. T. Chevassut

Brighton and Sussex Medical SchoolORCID 0000-0001-8672-1906Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrea G. S. PepperiD· 2 shared Benjamin P. TowleriD· 2 shared Chris J. PepperiD· 2 shared David A. PalmeriD· 2 shared Fabio A. SimoesiD· 2 shared John R JonesiD· 2 shared Kate J. HeesomiD· 2 shared Rhys G MorganiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Andrea G. S. PepperORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 30, 2026

RUNX1 aberrations in blast-phase CML induce the RBP SPATS2L which promotes growth, survival and stress granule assembly

David A. Palmer, Amy Lianne Muir, R Craig…·Rhys G Morgan

This study identifies SPATS2L as a mediator of growth and survival in RUNX1-mutant blast-phase CML through stress granule formation, suggesting it as a therapeutic target.

DOI 10.64898/2026.03.27.709496

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintDec 15, 2025

TOE1 influences canonical Wnt signalling in myeloid leukaemia cells through LEF-1 modulation and regulates the proliferation of haematopoietic cells through PAK2.

H. Park, O Sevim, M Wagstaff…·RG Morgan

This study identifies TOE1 as a novel β-catenin interactor in myeloid cells that modulates Wnt signaling via LEF-1 and regulates proliferation through PAK2.

1 citation

humanbulk RNA-seq

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Cancer BiologyCancersPeer-reviewedJan 3, 2025

A novel in-vitro model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance

Eleni E Ladikou, K. Sharp, Fabio A. Simoes…·Andrea G. S. Pepper

This study identifies CD44 and FAK as therapeutic targets to reverse adhesion-mediated drug resistance in AML by developing an in-vitro BMME model and testing their synergistic effects.

4 citations

humanbulk RNA-seq

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Systems BiologyBlood Cancer JournalPeer-reviewedJul 4, 2024

Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data.

Richard Norris, John R Jones, Erika J. Mancini…·Simon A. Mitchell

8 citations

humanwhole-exome sequencing

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