Benjamin P. Towler

This study identifies SPATS2L as a mediator of growth and survival in RUNX1-mutant blast-phase CML through stress granule formation, suggesting it as a therapeutic target.

This study identifies TOE1 as a novel β-catenin interactor in myeloid cells that modulates Wnt signaling via LEF-1 and regulates proliferation through PAK2.

The paper identifies β-catenin-associated mRNAs in myeloid cells through RIP-seq and shows MSI2 interacts with LEF1 mRNA, regulating Wnt signaling and HSPC expansion.

The paper characterizes miRNA expression in Drosophila wing imaginal discs and shows Pacman regulates the let-7 cluster, affecting apoptosis.

The paper identifies XRN1-sensitive transcripts in osteosarcoma cells and shows they contain G-rich motifs, suggesting XRN1 regulates lncRNAs involved in disease progression.

This study identifies Dis3L2 as a regulator of cell proliferation through a PI3-Kinase dependent pathway in both Drosophila and human cells.