Author

Isabelle Catherine Arnold

University of ZurichORCID 0000-0001-8679-9666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Hassan FazilatyiD· 3 shared Michael M. ScharliD· 3 shared Tomáš ValentaiD· 3 shared Deeksha RajuiD· 2 shared Kristina HandleriD· 2 shared Michael David BrüggeriD· 2 shared Tosca DalessiiD· 2 shared Zlatko TrajanoskiiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

Hassan FazilatyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BioinformaticsCancer CellPeer-reviewedJan 1, 2026

Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer

Valentin Marteau, Niloofar Nemati, Kristina Handler…·Zlatko Trajanoski

The paper integrates single-cell data from CRC patients to identify immune subtypes and neutrophil phenotypes, revealing their spatial organization and tumor-induced changes.

37 citationstop 1%

humanscRNA-seq

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Cancer BiologyGut MicrobesPeer-reviewedJul 20, 2025

Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease

Yasser Morsy, Ãsa Walberg, Paulina Wawrzyniak…·Michael M. Scharl

The paper identifies bacterial DNA remnants in blood immune cells of CRC and IBD patients, suggesting microbial translocation via intestinal barrier defects.

4 citations

humanmetagenomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 13, 2024

Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation

Kristina Handler, Deeksha Raju, Alessandra Gurtner…·Isabelle Catherine Arnold

This study shows eosinophils inhibit CRC metastasis by blocking SPP1+ macrophage differentiation, using transcriptomics and a murine model.

5 citations

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintOct 8, 2024

An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer

Tosca Dalessi, Tomáš Valenta, Giulia Moro…·Hassan Fazilaty

This study introduces oncoembryology to identify SoxC transcription factors as regulators of colon development and cancer, showing their role in tumor growth and metastasis.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky